Translation: Elongation

Translation elongation is simply the ribosome travelling down the message, reading codons and bringing in the proper aminoacyl tRNA’s to translate the message out to protein.  The incoming aminoacyl tRNA is brought into the ribosome A site, where it is matched with the codon being presented. Once it has been secured (by hydrolysis of GTP to “fix” it in place), the peptidyltransferase reaction occurs. This is where the bond between the peptide and the aminoacyl tRNA in the P site is broken, while a new bond is simultaneously formed between the (momentarily unattached) peptide and the new amino acid in the A site.  The ribosome then moves over by 3 bases, the spent tRNA is ejected from the E site.