Automatically Parcellating the Rat Brain

We use computer vision to segment rat brain regions from images of tissue sections stained for Nissl substance. Our practical goal is to deploy a method to parcellate brain tissue for neuroscience studies. The theoretical goal is to learn what features are important to a computer when segmenting brain regions. The computer vision methods are optimized by comparing their output with expert–drawn masks that delineate brain region boundaries in accordance with a standardized rat brain atlas, such as Brain Maps 4.0 .